Intact Dp Extra Tablets in Pakistan 03055997199 Lahore,Karachi,Sargodha
Intact Dp Extra Tablets in Pakistan
Intact Dp Extra Tablets in Pakistan tablets 100mg/60mg are used to treat erectile dysfunction (impotence) in men, which is inability to achieve or maintain a hard erect penis suitable for sexual activity, due to insufficient blood flow into the penis. Intact Dp Extra Tablets in Pakistan tablets relax the blood vessels in the penis increasing blood flow and causing an erection, which is the natural response to sexual stimulation. Intact Dp Extra Tablets in Pakistan tablets are also used to treat premature ejaculation, which is the most common sexual dysfunction in men of all ages, and is defined as early ejaculation with minimal sexual stimulation before of soon after penetration and can cause distress and problems with relationships. Intact Dp Extra Tablets in Pakistan tablets help improve control over ejaculation and increase the time interval before ejaculation occurs during intercourse, for men with persistent or recurrent premature ejaculation, by delaying the ejaculation process. Intact Dp Extra Tablets in Pakistan work by separate mechanism to remedy two sexual dysfunction disorders but will only work if you are sexually aroused.
How does Intact Dp Extra Tablets in Pakistan work?
Intact Dp Extra Tablets in Pakistan tablets 100mg/60mg contain sildenafil and dapoxetine, which are used in combination to treat erectile dysfunction and premature ejaculation. Sildenafil in Intact Dp Extra Tablets in Pakistan tablets acts on the erectile tissue of the penis to increase blood flow which causes an erection. During sexual stimulation nitric oxide is released in the erectile tissue of the penis which activates the enzyme guanylate cyclase. This enzyme increases levels of a chemical called cyclic guanosine monophosphate (cGMP), which relaxes the blood vessels in the penis and allows blood to fill the spongy erectile tissues to cause an erection. Another enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP preventing blood flow into the penis, which causes loss of an erection. Sildenafil in Intact Dp Extra Tablets in Pakistan tablets inhibit the action of PDE5 which resolves erectile dysfunction by allowing the natural process of sexual stimulation to activate the cGMP mechanism for achieving and maintaining an erection.
Dapoxetine in Intact Dp Extra Tablets in Pakistan tablets is a selective serotonin reuptake inhibitor (SSRI), which are normally used as antidepressants. However, dapoxetine has been specifically designed for treating premature ejaculation, as it has a rapid onset of action, with maximum effect within 1-2 hours and a short half-life, which means that it is rapidly eliminated from the body within 24 hours. Ejaculation is a reflex that is mediated by the sympathetic nervous system. When sexual stimulation has reached a certain threshold, sensory nerve cells in the spinal cord are activated and nerve impulses are sent to the brain, which then send messages back to motor neurones controlling the muscles in the penis that contract to effect ejaculation. The ejaculation reflex is thought to be mediated by serotonin, a specific brain chemical or neurotransmitter that is involved is transmitting nerve signals, which enables brain cells to communicate. Low levels of serotonin in certain areas of the brain are thought to contribute to premature ejaculation. Dapoxetine in Intact Dp Extra Tablets in Pakistan tablets blocks the reuptake of serotonin from the synapse, which is the gap between nerve cells across which chemical messages are sent from one nerve cell to another. If the re-uptake of serotonin by the first nerve cell (pre-synaptic) is blocked, this means that there is more serotonin remaining for the receiving nerve cell (post-synaptic), which allows nerve cells to communicate with each other for longer. This action of dapoxetine in Intact Dp Extra Tablets in Pakistan tablets helps prolong the ability to maintain sexual activity without premature ejaculation and maintain control over ejaculation for longer1.
Sildenafil and dapoxetine in Intact Dp Extra Tablets in Pakistan tablets work by different mechanisms of action to control two sexual dysfunction disorders2.
What does Intact Dp Extra Tablets in Pakistan contain?
Intact Dp Extra Tablets in Pakistan tablets contains the active ingredients sildenafil (100mg) and dapoxetine (60mg), which are used in combination to treat erectile dysfunction and premature ejaculation.
Treating sexual dysfunction with Intact Dp Extra Tablets in Pakistan
Intact Dp Extra Tablets in Pakistan tablets 100mg/60mg contain sildenafil and dapoxetine, which are used in combination to treat erectile dysfunction and premature ejaculation. Sildenafil in Intact Dp Extra Tablets in Pakistan tablets is a phosphodiesterase type 5 (PDE5) inhibitor, used to treat erectile dysfunction in men (impotence). It acts directly on the erectile tissue of the penis and works by inhibiting the breakdown, by the enzyme PDE5, of a chemical called cGMP, produced in the erectile tissue of the penis during sexual arousal, and this action increases blood flow into the penis causing an erection. Dapoxetine in Intact Dp Extra Tablets in Pakistan tablets is a selective serotonin reuptake inhibitor (SSRI) used to treat premature ejaculation. Premature ejaculation is reflex controlled by the brain neurotransmitter serotonin and low levels of serotonin are thought to contribute to premature ejaculation. Dapoxetine in Intact Dp Extra Tablets in Pakistan tablets blocks the reuptake of serotonin from the synapse, which is the gap between nerve cells across which chemical messages are sent from one nerve cell to another, which increases the amount of serotonin and allows nerve cells to communicate with each other for longer. This action of dapoxetine in Intact Dp Extra Tablets in Pakistan tablets helps prolong the ability to maintain sexual activity without premature ejaculation and maintain control over ejaculation for longer. When taken before planned sexual activity, Intact Dp Extra Tablets in Pakistan tablets work by different mechanisms of action to control two sexual dysfunction disorders.
What are the side effects of Intact Dp Extra Tablets in Pakistan?
The most commonly reported side effects when taking Intact Dp Extra Tablets in Pakistan tablets 100mg/60mg include headache, dizziness, nasal congestion, indigestion, nausea, diarrhoea, insomnia, fatigue flushing rash.
When should Intact Dp Extra Tablets in Pakistan not be used?
You should not use Intact Dp Extra Tablets in Pakistan tablets 100mg/60mg if you:
are allergic to sildenafil or dapoxetine or any ingredients in Intact Dp Extra Tablets in Pakistan
have abnormally high or low blood pressure
have an eye disease like non-arteritic anterior ischaemic optic neuropathy (NAION), which causes loss of vision or if you have retinitis pigmentosa
have a bleeding disorder
have depression, bipolar disorder, unstable epilepsy or schizophrenia
are taking any monoamine oxidase inhibitor medications as these can cause serious reactions if taken with Intact Dp Extra Tablets in Pakistan or within 14 days
are taking any nitrate medication, such as nitroglycerin for angina, as it may lead to a severe drop in blood pressure
are taking medicines that interact with Intact Dp Extra Tablets in Pakistan including
thioridazine for schizophrenia, monoamine oxidase inhibitors (MAOIs) for depression, migraine medicines like sumatriptan, the analgesic tramadol, SSRI antidepressants like paroxetine or citalopram, SNRI antidepressants like venlafaxine, lithium for mood disorders, calcium channel blockers like verapamil or diltiazem for hypertension, the anticoagulant warfarin, HIV treatments like ritonavir, saquinavir and atazanavir, antifungals like ketoconazole, antibiotics like erythromycin and rifampicin, NSAIDs like aspirin or ibuprofen, alpha-blockers like doxazosin for high blood pressure, cimetidine for treating ulcers, herbal remedies containing St. John´s Wort
What medications interact with Intact Dp Extra Tablets in Pakistan?
Several medications interact with Intact Dp Extra Tablets in Pakistan tablets 100mg/60mg and should either not be taken while you are taking Intact Dp Extra Tablets in Pakistan or only after discussion and instruction from your doctor:
Drugs that cause a serious reaction with Intact Dp Extra Tablets in Pakistan: any nitrate medication, such as nitroglycerin for angina, as it may lead to a severe drop in blood pressure, monoamine oxidase inhibitors for depression, thioridazine for schizophrenia, the anticoagulant warfarin increases risk of bleeding, NSAIDs like aspirin or ibuprofen St. John´s Wort, migraine medicines like sumatriptan, the analgesic tramadol, SSRI antidepressants like paroxetine or citalopram, SNRI antidepressants like venlafaxine, lithium for mood disorders
Drugs that affect Intact Dp Extra Tablets in Pakistan: thioridazine for schizophrenia, antifungals like ketoconazole, antibiotics like erythromycin, HIV treatments like ritonavir and atazanavir, calcium channel blockers like diltiazem for hypertension
Drugs that are affected by Intact Dp Extra Tablets in Pakistan: alpha-blockers like doxazosin for high blood pressure
How should Intact Dp Extra Tablets in Pakistan be taken?
You should take your Intact Dp Extra Tablets in Pakistan tablets 100mg/60mg swallowed whole with a glass of water with or without food and avoid alcohol. You should take your Intact Dp Extra Tablets in Pakistan tablets 1-3 hours before planned sexual activity. For premature ejaculation, Intact Dp Extra Tablets in Pakistan tablets will have maximum effect within 1-2 hours. For erectile dysfunction Intact Dp Extra Tablets in Pakistan tablets work will have maximum effect within 30 minutes and last for around 4 hours. You should not take more than one tablet in 24 hours and only if you plan to have sex.
How long should you take Intact Dp Extra Tablets in Pakistan?
You should only take Intact Dp Extra Tablets in Pakistan tablets 100mg/60mg when you plan to have sex; it is not intended as a regular medication.
How should Intact Dp Extra Tablets in Pakistan be stored?
You should store your Intact Dp Extra Tablets in Pakistan tablets 100mg/60mg below 25°C in a cool dry place.
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